PKC eta Antikörper (AA 30-389)

Produktnummer ABIN3043361

Produktdetails anti-PKC eta Antikörper

Target: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Bindungsspezifität: AA 30-389

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC eta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Protein kinase C eta type(PRKCH) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Protein kinase C eta type(PRKCH) detection. Tested with WB in Human.
Gene Name: protein kinase C, eta
Protein Name: Protein kinase C eta type

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PKC eta recombinant protein (Position: R30-D389). Human PKC eta shares 96.7% and 96.1% amino acid (aa) sequence identity with mouse and rat PKC eta, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-PKC eta Antikörper (ABIN3043361)

Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).

Details zu PKC eta

Target: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Andere Bezeichnung: PRKCH (PRKCH Produkte)

Synonyme: PKC-L antikoerper, PKCL antikoerper, PRKCL antikoerper, nPKC-eta antikoerper, Pkch antikoerper, pkc-eta antikoerper, PRKCH antikoerper, prkch antikoerper, si:ch211-212g7.5 antikoerper, zgc:172124 antikoerper, protein kinase C eta antikoerper, protein kinase C, eta antikoerper, protein kinase C eta L homeolog antikoerper, protein kinase C, eta, b antikoerper, protein kinase C, eta, a antikoerper, protein kinase C epsilon antikoerper, PRKCH antikoerper, Prkch antikoerper, prkch.L antikoerper, prkchb antikoerper, prkcha antikoerper, prkch antikoerper, PRKCE antikoerper

Hintergrund: PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Synonyms: KPCL_HUMAN antibody|MGC 5363 antibody|MGC26269 antibody|MGC5363 antibody|nPKC eta antibody| nPKC-eta antibody|PKC h antibody|PKC L antibody|PKC-L antibody|PKCh antibody|PKCL antibody| Prkch antibody|PRKCL antibody|Protein kinase C eta antibody|Protein kinase C eta type antibody

Gen-ID: 5583

UniProt: P24723

Pathways: Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling