SIRT6 Antikörper (AA 14-180)

Produktnummer ABIN3043435

Produktdetails anti-SIRT6 Antikörper

Target: SIRT6 (Sirtuin 6 (SIRT6))

Bindungsspezifität: AA 14-180

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-6(SIRT6) detection. Tested with WB, IHC-P in Human,Mouse.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-6(SIRT6) detection. Tested with WB, IHC-P in Human,Mouse.
Gene Name: sirtuin 6
Protein Name: NAD-dependent protein deacetylase sirtuin-6

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SIRT6 recombinant protein (Position: D14-E180). Human SIRT6 shares 95% amino acid (aa) sequence identity with mouse SIRT6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SIRT6 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu SIRT6

Target: SIRT6 (Sirtuin 6 (SIRT6))

Andere Bezeichnung: SIRT6 (SIRT6 Produkte)

Synonyme: 2810449N18Rik antikoerper, AI043036 antikoerper, Sir2l6 antikoerper, SIR2L6 antikoerper, zgc:86729 antikoerper, sirtuin 6 antikoerper, sirtuin 6 S homeolog antikoerper, Sirt6 antikoerper, SIRT6 antikoerper, sirt6.S antikoerper, sirt6 antikoerper

Hintergrund: SIRT6 is also known as SIR2L6. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

Synonyms: 2810449N18Rik antibody|AI043036 antibody|Mono ADP ribosyltransferase sirtuin 6 antibody|Mono-ADP-ribosyltransferase sirtuin-6 antibody|NAD-dependent deacetylase sirtuin-6 antibody|NAD-dependent protein deacetylase sirtuin-6 antibody|Regulatory proteinSIR2 homolog antibody|SIR2 like 6 antibody|SIR2 like protein 6 antibody|Sir2 related protein type 6 antibody|SIR2-like protein 6 antibody|SIR2L6 antibody|SIRT 6 antibody|SIRT6 antibody|SIRT6_HUMAN antibody|Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) antibody|Sirtuin 6 antibody|Sirtuin type 6 antibody|Sirtuin6 antibody

Gen-ID: 51548

UniProt: Q8N6T7