BAG2 Antikörper (AA 1-211)

Produktnummer ABIN3043508

Produktdetails anti-BAG2 Antikörper

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Bindungsspezifität: AA 1-211

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 2(BAG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 2(BAG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: BCL2-associated athanogene 2
Protein Name: BAG family molecular chaperone regulator 2

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human BAG2 recombinant protein (Position: M1-N211). Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Andere Bezeichnung: BAG2 (BAG2 Produkte)

Synonyme: bag2 antikoerper, MGC89300 antikoerper, BAG2 antikoerper, ATBAG2 antikoerper, BCL-2-associated athanogene 2 antikoerper, MTG10.13 antikoerper, MTG10_13 antikoerper, BAG-2 antikoerper, dJ417I1.2 antikoerper, zgc:64195 antikoerper, 2610042A13Rik antikoerper, BC016230 antikoerper, BCL2 associated athanogene 2 antikoerper, BCL-2-associated athanogene 2 antikoerper, BCL2-associated athanogene 2 antikoerper, Bcl2-associated athanogene 2 antikoerper, bag2 antikoerper, BAG2 antikoerper, Bag2 antikoerper

Hintergrund: BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.

Synonyms: BAG 2 antibody|BAG family molecular chaperone regulator 2 antibody|BAG-2 antibody|BAG-family molecular chaperone regulator-2 antibody|Bag2 antibody|BAG2_HUMAN antibody|BCL 2 associated athanogene 2 antibody|Bcl-2-associated athanogene 2 antibody|BCL2 associated athanogene 2 antibody|BCL2-associated athanogene 2 antibody|dJ417I1.2 (BAG family molecular chaperone regulator 2) antibody|dJ417I1.2 antibody|KIAA0576 antibody|MGC149462 antibody| OTTHUMP00000016668 antibody

Gen-ID: 9532

UniProt: O95816