Neuropilin 1 Antikörper (AA 504-827)

Produktnummer ABIN3043584

Produktdetails anti-Neuropilin 1 Antikörper

Target: Neuropilin 1 (NRP1)

Bindungsspezifität: AA 504-827

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuropilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Neuropilin-1(NRP1) detection. Tested with WB, IHC-P in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Neuropilin-1(NRP1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: neuropilin 1
Protein Name: Neuropilin-1

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for Neuropilin 1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Neuropilin 1 Antikörper (ABIN3043584)

Liu, Mei, Xu, Yu, Shi, Zhang, Wang, Zhang, Gao, Zhang, He: "Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy." in: Theranostics, Vol. 6, Issue 2, pp. 177-91, (2017) (PubMed).

Details zu Neuropilin 1

Target: Neuropilin 1 (NRP1)

Andere Bezeichnung: NRP1 (NRP1 Produkte)

Synonyme: NRP1 antikoerper, cd304 antikoerper, neuropilin antikoerper, np-1 antikoerper, npn-1 antikoerper, nrp antikoerper, nrp-1 antikoerper, vegf165r antikoerper, BDCA4 antikoerper, CD304 antikoerper, NP1 antikoerper, NRP antikoerper, VEGF165R antikoerper, C530029I03 antikoerper, NP-1 antikoerper, NPN-1 antikoerper, Npn1 antikoerper, Nrp antikoerper, neuropilin 1 antikoerper, neuropilin 1 L homeolog antikoerper, NRP1 antikoerper, nrp1 antikoerper, Nrp1 antikoerper, nrp1.L antikoerper

Hintergrund: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Synonyms: A5 protein antibody|BDCA4 antibody|BLOOD DENDRITIC CELL ANTIGEN 4 antibody|CD 304 antibody|CD304 antibody|DKFZp686A03134 antibody|DKFZp781F1414 antibody|Neuropilin-1 antibody|Neuropilin1 antibody|Neuropilin1 transmembrane receptor antibody|NP1 antibody|NPN1 antibody|NRP 1 antibody|NRP antibody|NRP1 antibody|NRP1_HUMAN antibody|Vascular endothelial cell growth factor 165 receptor antibody|VEGF165R antibody

Gen-ID: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals