BUB1 Antikörper (AA 731-1085)

Produktnummer ABIN3043764

Produktdetails anti-BUB1 Antikörper

Target: BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

Bindungsspezifität: AA 731-1085

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BUB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Mitotic checkpoint serine/threonine-protein kinase BUB1(BUB1) detection. Tested with WB in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Mitotic checkpoint serine/threonine-protein kinase BUB1(BUB1) detection. Tested with WB in Human,Rat.
Gene Name: BUB1 mitotic checkpoint serine/threonine kinase
Protein Name: Mitotic checkpoint serine/threonine-protein kinase BUB1

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Bub1 recombinant protein (Position: V731-K1085). Human Bub1 shares 81% amino acid (aa) sequence identity with mouse Bub1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for Bub1 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu BUB1

Target: BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

Andere Bezeichnung: BUB1 (BUB1 Produkte)

Synonyme: bub1a antikoerper, bub1l antikoerper, hbub1 antikoerper, xbub1 antikoerper, BUB1A antikoerper, BUB1L antikoerper, hBUB1 antikoerper, AL022991 antikoerper, Bub1a antikoerper, C80208 antikoerper, D2Xrf87 antikoerper, BUB1 mitotic checkpoint serine/threonine kinase antikoerper, BUB1, mitotic checkpoint serine/threonine kinase antikoerper, BUB1 antikoerper, bub1 antikoerper, Bub1 antikoerper

Hintergrund: BUB1, also known as mitotic checkpoint serine/threonine kinase, is an enzyme that in humans is encoded by the BUB1 gene. It is mapped to 2q13. BUB1 is first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of BUB1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence. The protein kinase BUB1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome alignment during metaphase.

Synonyms: Bub1 antibody|BUB1 budding uninhibited by benzimidazoles 1 homolog antibody|BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) antibody|BUB1 mitotic checkpoint serine/threonine kinase antibody|BUB1, S. cerevisiae, homolog of antibody|BUB1_HUMAN antibody|BUB1A antibody|BUB1L antibody|Budding uninhibited by benzimidazoles 1 (yeast homolog) antibody|Budding uninhibited by benzimidazoles 1 homolog antibody|Budding uninhibited by benzimidazoles 1, S. cerevisiae, homolog of antibody|hBUB1 antibody|Homolog of mitotic checkpoint gene BUB1 antibody|Mitotic checkpoint gene BUB1 antibody|Mitotic checkpoint serine/threonine protein kinase BUB1 antibody|Mitotic checkpoint serine/threonine-protein kinase BUB1 antibody|Mitotic spindle checkpoint kinase antibody|Putative serine/threonine protein kinase antibody

Gen-ID: 699

UniProt: O43683