Peroxiredoxin 5 Antikörper (AA 66-198)

Produktnummer ABIN3043906

Produktdetails anti-Peroxiredoxin 5 Antikörper

Target: Peroxiredoxin 5 (PRDX5)

Bindungsspezifität: AA 66-198

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Peroxiredoxin-5, mitochondrial(PRDX5) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Peroxiredoxin-5, mitochondrial(PRDX5) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: peroxiredoxin 5
Protein Name: Peroxiredoxin-5, mitochondrial

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Peroxiredoxin 5 recombinant protein (Position: E66-D198). Human Peroxiredoxin 5 shares 91% amino acid (aa) sequence identity with both mouse and rat Peroxiredoxin 5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Peroxiredoxin 5 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Peroxiredoxin 5

Target: Peroxiredoxin 5 (PRDX5)

Andere Bezeichnung: PRDX5 (PRDX5 Produkte)

Synonyme: acr1 antikoerper, aoeb166 antikoerper, pmp20 antikoerper, prx-5 antikoerper, prx5 antikoerper, prxv antikoerper, sbbi10 antikoerper, GB16965 antikoerper, zgc:112318 antikoerper, PRDX5 antikoerper, CG 32920 antikoerper, CG 7217 antikoerper, CG32920 antikoerper, CG7217 antikoerper, Dmel\\CG7217 antikoerper, dPrx5 antikoerper, dprx5 antikoerper, ACR1 antikoerper, AOEB166 antikoerper, B166 antikoerper, PLP antikoerper, PMP20 antikoerper, PRDX6 antikoerper, PRXV antikoerper, prx-V antikoerper, AOPP antikoerper, Pmp20 antikoerper, Prdx6 antikoerper, PrxV antikoerper, Aoeb166 antikoerper, Prx V antikoerper, peroxiredoxin 5 L homeolog antikoerper, peroxiredoxin-5, mitochondrial antikoerper, peroxiredoxin 5 antikoerper, Peroxiredoxin 5 antikoerper, prdx5.L antikoerper, LOC552429 antikoerper, prdx5 antikoerper, PRDX5 antikoerper, Prx5 antikoerper, Prdx5 antikoerper

Hintergrund: PRDX5 (peroxiredoxin 5) also known as AOEB166, ACR1,B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes. The PRDX5 gene is mapped to11q13.1. PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence. Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell lines. Functional analysis showed that PRDX5 has antioxidant activity equivalent to that of CAT. While PRDX5 was localized to fibroblasts in normal tendon, it was localized to fibroblasts and endothelial cells in degenerative tendon. PRDX5 mRNA and protein levels increased at 12 hours, and the increase in PRDX5 expression correlated with reduced peroxide levels. PRDX5 plays a protective role against oxidative stress in human cartilage.

Synonyms: ACR 1 antibody|ACR1 antibody|Alu co repressor 1 antibody|Alu co-repressor 1 antibody|Alu corepressor 1 antibody|antioxidant enzyme B166 antibody|AOEB166 antibody|B166 antibody|liver tissue 2D-page spot 71B antibody|MGC117264 antibody|MGC142283 antibody|MGC142285 antibody|mitochondrial antibody|Peroxiredoxin 5 mitochondrial antibody|Peroxiredoxin 5, mitochondrial antibody|Peroxiredoxin V antibody|Peroxiredoxin-5 antibody|Peroxiredoxin5 antibody|peroxisomal antioxidant enzyme antibody|PLP antibody|PMP 20 antibody|PMP20 antibody|PRDX 5 antibody|PRDX 6 antibody|PRDX5 antibody|PRDX5_HUMAN antibody|PRDX6 antibody|Prx V antibody|Prx-V antibody|PRXV antibody|SBBI10 antibody|thioredoxin peroxidase PMP20 antibody|Thioredoxin reductase antibody|TPx type VI antibody

Gen-ID: 25824

UniProt: P30044

Pathways: Cell RedoxHomeostasis