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YBX1 Antikörper (C-Term)

YBX1 Reaktivität: Human, Ratte, Maus WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043966
  • Target Alle YBX1 Antikörper anzeigen
    YBX1 (Y Box Binding Protein 1 (YBX1))
    Bindungsspezifität
    • 25
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 293-320, C-Term
    Reaktivität
    • 111
    • 75
    • 62
    • 21
    • 19
    • 18
    • 17
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 102
    • 11
    Kaninchen
    Klonalität
    • 94
    • 19
    Polyklonal
    Konjugat
    • 54
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser YBX1 Antikörper ist unkonjugiert
    Applikation
    • 80
    • 24
    • 17
    • 15
    • 14
    • 14
    • 13
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Nuclease-sensitive element-binding protein 1(YBX1) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
    Sequenz
    ENPKPQDGKE TKAADPPAEN SSAPEAEQ
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Nuclease-sensitive element-binding protein 1(YBX1) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
    Gene Name: Y box binding protein 1
    Protein Name: Nuclease-sensitive element-binding protein 1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human YB1 (293-320aa ENPKPQDGKETKAADPPAENSSAPEAEQ), identical to the related mouse and rat sequences.
    Isotyp
    IgG
    Top Product
    Discover our top product YBX1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for YB1 is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    YBX1 (Y Box Binding Protein 1 (YBX1))
    Andere Bezeichnung
    YBX1 (YBX1 Produkte)
    Synonyme
    BP-8 antikoerper, CSDA2 antikoerper, CSDB antikoerper, DBPB antikoerper, MDR-NF1 antikoerper, NSEP-1 antikoerper, NSEP1 antikoerper, YB-1 antikoerper, YB1 antikoerper, Byb1 antikoerper, Cbfa antikoerper, Dbpb antikoerper, Ef1a antikoerper, Msy1 antikoerper, Nsep1 antikoerper, Yb1 antikoerper, bp-8 antikoerper, csda2 antikoerper, csdb antikoerper, dbpb antikoerper, frgy1 antikoerper, mdr-nf1 antikoerper, nsep-1 antikoerper, nsep1 antikoerper, yb1 antikoerper, 1700102N10Rik antikoerper, C79409 antikoerper, EF1A antikoerper, MSY1 antikoerper, dbpB antikoerper, mYB-1a antikoerper, nuclease sensitive element binding protein 1 antikoerper, Y-box binding protein 1 antikoerper, Y box binding protein 1 antikoerper, Y-box binding protein 1 S homeolog antikoerper, nuclease-sensitive element-binding protein 1 antikoerper, Y box protein 1 antikoerper, nsep1 antikoerper, YBX1 antikoerper, Ybx1 antikoerper, ybx1.S antikoerper, LOC479011 antikoerper
    Hintergrund
    YBX1(Y box binding protein 1), commonly referred to as "YB-1" by researchers, is a human protein. YB1 binding has an absolute requirement for the CCAAT box and relative specificity for the Y box. It has a molecular mass of 35,414 and contains 18 % basic residues and putative nuclear localization signals. The YBX1 gene is mapped on 1p34.2. Ybx1 was highly expressed in mouse erythroid myeloid lymphoid clone-1 (EML), a hematopoietic precursor cell line, but that it was downregulated in myeloid progenitors and in Gmcsf-treated EML cells during myeloid differentiation. Ybx1 was expressed at high levels in myeloid leukemic cells at different developmental stages. Knockdown of YBX1 in a human leukemic cell line inhibited proliferation ability, induced apoptosis, and induced megakaryocytic differentiation in response to arsenic trioxide treatment. YBX1 is downregulated during myeloid differentiation and aberrant YBX1 expression in leukemic cells may contribute to leukemia development by blocking differentiation.

    Synonyms: BP 8 antibody|CBF-A antibody|CCAAT binding transcription factor I subunit A antibody|CCAAT-binding transcription factor I subunit A antibody|CSDA2 antibody|CSDB antibody|DBPB antibody|DNA binding protein B antibody|DNA-binding protein B antibody|EFI-A antibody| Enhancer factor I subunit A antibody|MDR NF1 antibody|MGC104858 antibody|MGC110976 antibody|MGC117250 antibody|NSEP 1 antibody|NSEP1 antibody|Nuclease sensitive element binding protein 1 antibody|Nuclease-sensitive element-binding protein 1 antibody|p50 antibody|Q15905 antibody|Y-box binding protein 1 antibody|Y-box transcription factor antibody|Y-box-binding protein 1 antibody|YB 1 antibody|YB-1 antibody|YBOX1_HUMAN antibody| YBX 1 antibody|YBX1 antibody
    Gen-ID
    4904
    UniProt
    P67809
    Pathways
    Regulation of Muscle Cell Differentiation
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