CCR3 Antikörper (N-Term)

Produktnummer ABIN3043996

Produktdetails anti-CCR3 Antikörper

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Bindungsspezifität: AA 1-20, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Verwendungszweck: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 3(CCR3) detection. Tested with WB, IHC-P, ICC in Human.

Sequenz: MTTSLDTVET FGTTSYYDDV

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 3(CCR3) detection. Tested with WB, IHC-P, ICC in Human.
Gene Name: chemokine(C-C motif) receptor 3
Protein Name: C-C chemokine receptor type 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CCR3(1-20aa MTTSLDTVETFGTTSYYDDV).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CCR3

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Andere Bezeichnung: CCR3 (CCR3 Produkte)

Synonyme: CC-CKR-3 antikoerper, CD193 antikoerper, CKR3 antikoerper, CMKBR3 antikoerper, CC-CKR3 antikoerper, Cmkbr1l2 antikoerper, Cmkbr3 antikoerper, C-C motif chemokine receptor 3 antikoerper, chemokine (C-C motif) receptor 3 antikoerper, CCR3 antikoerper, Ccr3 antikoerper

Hintergrund: C-C chemokine receptor type 3, also called CCR3 or CKR3 is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, including eotaxin(CCL11), eotaxin-3(CCL26), MCP-3(CCL7), MCP-4(CCL13), and RANTES(CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described.

Synonyms: B Chemokine Receptor antibody|b-chemokine receptor antibody|C C chemokine receptor type 3 antibody|C C CKR 3 antibody|C-C chemokine receptor type 3 antibody|C-C CKR-3 antibody|CC Chemokine Receptor 3 antibody|CC chemokine receptor type 3 antibody|CC CKR 3 antibody|CC R3 antibody|CC-CKR-3 antibody|CCCKR3 antibody|CCR 3 antibody|CCR-3 antibody|CCR3 antibody|CCR3_HUMAN antibody|CD 193 antibody|CD193 antibody|CD193 antigen antibody|Chemokine(C C motif) receptor 3 antibody|chemokine(C-C motif) receptor 3 antibody|Chemokine(CC) Receptor 1 Like 2 antibody|Chemokine CC Motif Receptor 3 antibody|Chemokine receptor 3 antibody|CK R3 antibody|CKR 3 antibody|CKR3 antibody|CMKB R3 antibody|CMKBR 3 antibody|CMKBR1L2 antibody|CMKBR3 antibody|Eosinophil CC Chemokine Receptor 3 antibody|Eosinophil Eotaxin Receptor antibody|Eotaxin Receptor antibody|Macrophage inflammatory protein 1 alpha receptor like 2 antibody|Macrophage Inflammatory Protein1 Alpha Receptor Like 2 antibody|MGC102841 antibody|MIP1 Alpha RL2 antibody

UniProt: P51677