EGR1 Antikörper (N-Term)

Produktnummer ABIN3043997

Produktdetails anti-EGR1 Antikörper

Target: EGR1 (Early Growth Response 1 (EGR1))

Bindungsspezifität: AA 23-43, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Rabbit IgG polyclonal antibody for Early growth response protein 1(EGR1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.

Sequenz: FPHSPTMDNY PKLEEMMLLS N

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Early growth response protein 1(EGR1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: early growth response 1
Protein Name: Early growth response protein 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Egr1(23-43aa FPHSPTMDNYPKLEEMMLLSN), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-EGR1 Antikörper (ABIN3043997)

Lin, Fang, Cai, Huang, Zhang, Lu, Zhang, Wei: "ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." in: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).

Details zu EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Andere Bezeichnung: EGR1 (EGR1 Produkte)

Synonyme: AT225 antikoerper, G0S30 antikoerper, KROX-24 antikoerper, NGFI-A antikoerper, TIS8 antikoerper, ZIF-268 antikoerper, ZNF225 antikoerper, A530045N19Rik antikoerper, ETR103 antikoerper, Egr-1 antikoerper, Krox-1 antikoerper, Krox-24 antikoerper, Krox24 antikoerper, NGF1-A antikoerper, NGFIA antikoerper, Zenk antikoerper, Zfp-6 antikoerper, Zif268 antikoerper, egr antikoerper, Ngf1 antikoerper, Ngfi antikoerper, zif-268 antikoerper, EGR1 antikoerper, EGR-1-A antikoerper, Xegr-1 antikoerper, at225 antikoerper, egr-1 antikoerper, egr1 antikoerper, g0s30 antikoerper, krox-24 antikoerper, ngfi-a antikoerper, tis8 antikoerper, znf225 antikoerper, krox24 antikoerper, wu:fj64b05 antikoerper, wu:fq25f01 antikoerper, EGR-1 antikoerper, zenk antikoerper, EGR-1-B antikoerper, egr1-a antikoerper, egr1-b antikoerper, early growth response 1 antikoerper, early growth response protein 1 (egr-1) antikoerper, early growth response 1 L homeolog antikoerper, early growth response 1 S homeolog antikoerper, EGR1 antikoerper, CNK00890 antikoerper, Egr1 antikoerper, egr1.L antikoerper, egr1 antikoerper, egr1.S antikoerper

Hintergrund: Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.

Synonyms: AT 225 antibody|AT225 antibody|Early growth response 1 antibody|Early growth response protein 1 antibody|EGR 1 antibody|EGR-1 antibody|EGR1 antibody|EGR1_HUMAN antibody|G0S 30 antibody|G0S30 antibody|KROX 24 antibody|Krox 24 protein antibody|KROX24 antibody|Nerve growth factor induced protein A antibody|Nerve growth factor-induced clone A antibody|Nerve growth factor-induced protein A antibody|NGFI A antibody|NGFI-A antibody|NGFIA antibody|TIS 8 antibody|TIS8 antibody|Transcription factor ETR 103 antibody|Transcription factor ETR103 antibody|Transcription factor Zif 268 antibody|Transcription factor Zif268 antibody|Zfp 6 antibody|ZIF 268 antibody|ZIF268 antibody|Zinc finger protein 225 antibody|Zinc finger protein Krox-24 antibody|ZNF 225 antibody|ZNF225 antibody

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity