HSD17B4 Antikörper (C-Term)

Produktnummer ABIN3044284

Produktdetails anti-HSD17B4 Antikörper

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Bindungsspezifität: AA 744-761, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Peroxisomal multifunctional enzyme type 2(HSD17B4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: NIMLSQKLQM ILKDYAKL

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Peroxisomal multifunctional enzyme type 2(HSD17B4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: hydroxysteroid(17-beta) dehydrogenase 4
Protein Name: Peroxisomal multifunctional enzyme type 2

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Hydroxysteroid(17-beta) Dehydrogenase 4(744-761aa NIMLSQKLQMILKDYAKL), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Andere Bezeichnung: HSD17B4 (HSD17B4 Produkte)

Synonyme: zgc:55545 antikoerper, zgc:77300 antikoerper, CG3415 antikoerper, DmMFE-2 antikoerper, Dmel\\CG3415 antikoerper, MFE-2 antikoerper, DBP antikoerper, MPF-2 antikoerper, PRLTS1 antikoerper, SDR8C1 antikoerper, 17-beta-HSD antikoerper, 17[b]-HSD antikoerper, 4 antikoerper, MFP2 antikoerper, Mfp-2 antikoerper, perMFE-2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 4 antikoerper, hydroxysteroid 17-beta dehydrogenase 4 antikoerper, peroxisomal Multifunctional enzyme type 2 antikoerper, hsd17b4 antikoerper, HSD17B4 antikoerper, Mfe2 antikoerper, Hsd17b4 antikoerper

Hintergrund: Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms: 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase antibody|17 beta HSD 4 antibody|17 beta HSD IV antibody|17 beta hydroxysteroid dehydrogenase 4 antibody|17-beta-HSD 4 antibody|17-beta-hydroxysteroid dehydrogenase 4 antibody|17beta estradiol dehydrogenase type IV antibody|3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase antibody|3-alpha antibody|7-alpha antibody|Beta hydroxyacyl dehydrogenase antibody|Beta keto reductase antibody|D 3 hydroxyacyl CoA dehydratase antibody|D bifunctional protein antibody|D bifunctional protein peroxisomal antibody|D-bifunctional protein antibody|DBP antibody|DHB4_HUMAN antibody|EDH17B4 antibody|Enoyl-CoA hydratase 2 antibody|Hsd17b4 antibody|MFE 2 antibody|MFE-2 antibody|MPF-2 antibody|Multifunctional protein 2 antibody|Peroxisomal multifunctional enzyme type 2 antibody|Peroxisomal multifunctional protein 2 antibody|SDR8C1 antibody|Short chain dehydrogenase/reductase family 8C member 1 antibody

Pathways: Monocarboxylic Acid Catabolic Process