Apoptosis Inhibitor 5 Antikörper (C-Term)

Produktnummer ABIN3044316

Produktdetails anti-Apoptosis Inhibitor 5 Antikörper

Target: Apoptosis Inhibitor 5 (API5)

Bindungsspezifität: AA 487-504, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apoptosis Inhibitor 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Rabbit IgG polyclonal antibody for Apoptosis inhibitor 5(API5) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.

Sequenz: KYSSNLGNFN YERSLQGK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Apoptosis inhibitor 5(API5) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: apoptosis inhibitor 5
Protein Name: Apoptosis inhibitor 5(API-5)

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Apoptosis inhibitor 5(487-504aa KYSSNLGNFNYERSLQGK)(b), different from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Andere Bezeichnung: API5 (API5 Produkte)

Synonyme: AAC-11 antikoerper, AAC11 antikoerper, AI196452 antikoerper, api5l1 antikoerper, sr:nyz021 antikoerper, zgc:66211 antikoerper, wu:fb26c03 antikoerper, API-5B antikoerper, aac-11 antikoerper, aac11 antikoerper, api5 antikoerper, API-5A antikoerper, api5-A antikoerper, MGC83290 antikoerper, API5 antikoerper, apoptosis inhibitor 5 antikoerper, apoptosis inhibitor 5 S homeolog antikoerper, apoptosis inhibitor 5 L homeolog antikoerper, API5 antikoerper, Api5 antikoerper, api5 antikoerper, api5.S antikoerper, api5.L antikoerper

Hintergrund: Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death(apoptosis). Apoptosis inhibitor 5(API5) is an antiapoptotic factor which may have a role in protein assembly. The API5 gene to chromosome 11p12 based on an alignment of the API5 sequence with the genomic sequence It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.

Synonyms: AAC 11 antibody|AAC-11 antibody|AAC11 antibody|Antiapoptosis clone 11 protein antibody|API 5 antibody|API-5 antibody|API5 antibody|API5 like 1 antibody|API5_HUMAN antibody|API5L1 antibody|Apoptosis inhibitor 5 antibody|Cell migration inducing gene 8 protein antibody|Cell migration-inducing gene 8 protein antibody|Fibroblast growth factor 2 interacting factor 2 antibody|Fibroblast growth factor 2-interacting factor antibody|FIF antibody|MIG 8 antibody|MIG8 antibody|Migration inducing protein MIG8 antibody|Protein XAGL antibody

Pathways: Growth Factor Binding