ONECUT1 Antikörper (N-Term)

Produktnummer ABIN3044467

Produktdetails anti-ONECUT1 Antikörper

Target: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Bindungsspezifität: AA 187-203, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ONECUT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Rabbit IgG polyclonal antibody for Hepatocyte nuclear factor 6(ONECUT1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.

Sequenz: LGSIHNSQQG LPHYAHP

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Hepatocyte nuclear factor 6(ONECUT1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: one cut homeobox 1
Protein Name: Hepatocyte nuclear factor 6

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HNF6(187-203aa LGSIHNSQQGLPHYAHP), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ONECUT1

Target: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Andere Bezeichnung: ONECUT1 (ONECUT1 Produkte)

Synonyme: D9Ertd423e antikoerper, HNF-6 antikoerper, Hfh12 antikoerper, Hnf6 antikoerper, Hnf6b antikoerper, OC-1 antikoerper, Oc1 antikoerper, onecut antikoerper, onecut1 antikoerper, id:ibd5005 antikoerper, HNF6 antikoerper, HNF6A antikoerper, HNF-6a antikoerper, oc1 antikoerper, onecut1l antikoerper, zgc:65904 antikoerper, zgc:77450 antikoerper, one cut domain, family member 1 antikoerper, one cut homeobox 1 antikoerper, one cut domain, family member, like antikoerper, Onecut1 antikoerper, onecutl antikoerper, ONECUT1 antikoerper, onecut1 antikoerper

Hintergrund: One cut homeobox 1(ONECUT1), also called Hepatocyte nuclear factor 6(HNF6) is found strong expression in liver and lower expression in testis and skin. ONECUT1 gene is mapped to 15q21.3. This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer.

Synonyms: Hepatocyte nuclear factor 6 antibody|HNF 6 antibody|HNF6A antibody|One cut domain family member 1 antibody|Onecut1 antibody