Fatty Acid Synthase Antikörper (AA 1-226)

Produktnummer ABIN3044520

Produktdetails anti-Fatty Acid Synthase Antikörper

Target: Fatty Acid Synthase (FASN)

Bindungsspezifität: AA 1-226

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fatty Acid Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Fatty acid synthase(FASN) detection. Tested with WB, IHC-P in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Fatty acid synthase(FASN) detection. Tested with WB, IHC-P in Human.
Gene Name: fatty acid synthase
Protein Name: Fatty acid synthase

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Fatty Acid Synthase Antikörper (ABIN3044520)

Lu, Ma, Cai: "Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis." in: Tumour biology, Vol. 39, Issue 4, pp. 1010428317697570, (2017) (PubMed).

Details zu Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Andere Bezeichnung: FASN (FASN Produkte)

Synonyme: FAS antikoerper, OA-519 antikoerper, SDR27X1 antikoerper, FASN antikoerper, fj34h12 antikoerper, wu:fj34h12 antikoerper, Cgl0836 antikoerper, A630082H08Rik antikoerper, BcDNA:GH07626 antikoerper, BcDNA:gh07626 antikoerper, DM_7295848 antikoerper, Dmel\\CG3523 antikoerper, Fatty acid synthase antikoerper, anon-EST:Posey235 antikoerper, anon-EST:Posey43 antikoerper, anon-WO0138581.1 antikoerper, dFAS antikoerper, fas antikoerper, fatty acid synthase antikoerper, fatty acid synthase Fas antikoerper, type I polyketide synthase antikoerper, Fatty acid synthase Fas antikoerper, Fatty Acid SyNthase antikoerper, fatty-acid synthase antikoerper, fatty-acid synthase II antikoerper, fatty-acid synthase fas antikoerper, Fatty acid synthase 1 antikoerper, FASN antikoerper, fas antikoerper, Fasn antikoerper, BAD_RS01360 antikoerper, fasn antikoerper, fasn-1 antikoerper, NCgl0802 antikoerper, fasB antikoerper, MT2600 antikoerper, TBMG_01448 antikoerper, FASN1 antikoerper

Hintergrund: Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Synonyms: [Acyl-carrier-protein] S acetyltransferase antibody|[Acyl-carrier-protein] S malonyltransferase antibody|3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase antibody|3-oxoacyl-[acyl-carrier-protein] reductase antibody|3-oxoacyl-[acyl-carrier-protein] synthase antibody|Enoyl-[acyl-carrier-protein] reductase antibody|FAS antibody|FAS_HUMAN antibody|FASN antibody|Fatty acid synthase antibody| MGC14367 antibody|MGC15706 antibody|OA 519 antibody|Oleoyl-[acyl-carrier-protein] hydrolase antibody|SDR27X1 antibody|Short chain dehydrogenase/reductase family 27X member 1 antibody

Gen-ID: 2194

UniProt: P49327

Pathways: AMPK Signaling