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TPP1 Antikörper (Middle Region)

TPP1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044554
  • Target Alle TPP1 Antikörper anzeigen
    TPP1 (Tripeptidyl Peptidase I (TPP1))
    Bindungsspezifität
    • 15
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 227-261, Middle Region
    Reaktivität
    • 65
    • 26
    • 11
    Human
    Wirt
    • 60
    • 5
    • 1
    Kaninchen
    Klonalität
    • 63
    • 3
    Polyklonal
    Konjugat
    • 28
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TPP1 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 26
    • 13
    • 13
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Tripeptidyl-peptidase 1(TPP1) detection. Tested with WB, IHC-P in Human.
    Sequenz
    CAQFLEQYFH DSDLAQFMRL FGGNFAHQAS VARVV
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Tripeptidyl-peptidase 1(TPP1) detection. Tested with WB, IHC-P in Human.
    Gene Name: tripeptidyl peptidase I
    Protein Name: Tripeptidyl-peptidase 1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human TPP1 (227-261aa CAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVV), different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product TPP1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    TPP1 (Tripeptidyl Peptidase I (TPP1))
    Andere Bezeichnung
    TPP1 (TPP1 Produkte)
    Synonyme
    cln2 antikoerper, fa01b09 antikoerper, im:7149243 antikoerper, wu:fa01b09 antikoerper, CLN2 antikoerper, LPIC antikoerper, TPP-1 antikoerper, TPP-I antikoerper, Cln2 antikoerper, tripeptidyl peptidase I antikoerper, tripeptidyl-peptidase 1 antikoerper, tripeptidyl peptidase 1 antikoerper, tpp1 antikoerper, NAEGRDRAFT_78259 antikoerper, MCYG_00184 antikoerper, MGYG_05881 antikoerper, MGYG_00757 antikoerper, TPP1 antikoerper, Tpp1 antikoerper
    Hintergrund
    Tripeptidyl-peptidase 1, also known as Lysosomal pepstatin-insensitive protease, is an enzyme that in humans is encoded by the TPP1 gene. This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

    Synonyms: Cell growth inhibiting gene 1 protein antibody|Cell growth-inhibiting gene 1 protein antibody|Ceroid lipofuscinosis neuronal 2 antibody|Ceroid lipofuscinosis neuronal 2 late infantile (Jansky Bielschowsky disease) antibody|Ceroid lipofuscinosis neuronal 2 late infantile antibody|CLN 2 antibody|CLN2 antibody|GIG 1 antibody|GIG1 antibody|Growth inhibiting protein 1 antibody|LPIC antibody| Lysosomal pepstatin insensitive protease antibody|Lysosomal pepstatin-insensitive protease antibody|MGC21297 antibody|TPP 1 antibody| TPP I antibody|TPP-1 antibody|TPP-I antibody|Tpp1 antibody|TPP1_HUMAN antibody|TPPI antibody|Tripeptidyl aminopeptidase antibody| Tripeptidyl peptidase I antibody|Tripeptidyl-peptidase 1 antibody|Tripeptidyl-peptidase I antibody
    Gen-ID
    1200
    UniProt
    O14773
    Pathways
    Zellzyklus, ER-Nucleus Signaling
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