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p53 Antikörper

Name: p53 Antikörper
SKU: ABIN306557
Price: 461.03 EUR
Availability: InStock

TP53 Reaktivität: Human, Maus, Ratte WB Wirt: Schaf Polyclonal unconjugated

Each lane contains 50µg of total cellular protein separated by 10% SDS-PAGE. (p53 Antikörper)

1 image

Produktnummer ABIN306557

Datenblatt (PDF)

Target Alle p53 (TP53) Antikörper anzeigen

p53 (TP53) (Tumor Protein P53 (TP53))
Reaktivität
834

254

210

107

50

34

33

19

10

9

7

6

6

3

3

3

3

2

2

2

2

1

1

1
Human, Maus, Ratte
Wirt
623

229

5

2

1
Schaf
Klonalität
558

301

1
Polyklonal
Konjugat
484

38

32

19

19

13

13

13

13

13

13

13

13

13

12

12

11

11

11

11

11

11

11

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser p53 Antikörper ist unkonjugiert
Applikation
667

298

250

202

200

149

128

124

119

68

59

35

18

16

13

12

9

9

8

6

4

3

3

3

3

2

2

2

1

1

1

1

1
Western Blotting (WB)

Isotyp

IgG

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TP53 Reaktivität: Human WB, ELISA, IF, IHC (p), IP Wirt: Maus Monoclonal 2C3 unconjugated

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TP53 Reaktivität: Human WB, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 2C11 unconjugated

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Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/ml

Lagerung

-20 °C
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Andere Bezeichnung

p53 (TP53 Produkte)

Hintergrund

GST p53 fusion protein containing amino acids 1-393 of human p53was used as immunogen. p53 has a molecular weight of 53kDa p53 is a transcription factor that can inhibit cell cycle progression or induce apoptosis in response to stress or DNA damage. Disruption of the p53 signalling pathway through various mechanisms is the most common alteration in human cancer occuring in over half of all tumors. The p53 protein is short lived and expressed at low levels in normal cells but accumulates and/or is activated in cells that have undergone genotoxic damage or oncogene activation. Many tumor derived and transformed cell lines express elevated levels of mutant p53 protein. Synonyms: Sheep anti human p53, hp53.

UniProt

P04637

Pathways

p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt