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SH3BP2 Antikörper

SH3BP2 Reaktivität: Maus WB Wirt: Schaf Polyclonal unconjugated
Produktnummer ABIN306729
  • Target Alle SH3BP2 Antikörper anzeigen
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Reaktivität
    • 40
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 36
    • 4
    Schaf
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SH3BP2 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 20
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus
    Produktmerkmale
    Sh3bp2, SH3 domain-binding protein 2,3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66 % homologous to the human protein at the amino acid level.
    Aufreinigung
    Ammonium Sulfate Precipitation
    Immunogen
    Antibody developed using SH2 domain of the 3BP2 protein fused to GST.
    Isotyp
    IgG
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  • Applikationshinweise
    Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Optimal concentration should be evaluated by serial dilutions.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • Target
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Andere Bezeichnung
    3BP2 (SH3 Binding Protein 2) (SH3BP2 Produkte)
    Synonyme
    SH3BP2 antikoerper, 3BP-2 antikoerper, 3BP2 antikoerper, CRBM antikoerper, CRPM antikoerper, SH3 domain binding protein 2 antikoerper, SH3-domain binding protein 2 antikoerper, SH3BP2 antikoerper, Sh3bp2 antikoerper
    UniProt
    Q06649
    Pathways
    T-Zell Rezeptor Signalweg
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