CD38 Antikörper (Biotin)

Produktnummer ABIN3071825

Produktdetails anti-CD38 Antikörper (Biotin)

Target: CD38

Reaktivität: Human, Pavian, Cynomolgus, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD38 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Verwendungszweck: CD38 Biotin Antibody

Produktmerkmale: The clone OKT10, a mouse monoclonal antibody, recognizes a 45 kDa, type II transmembrane cell surface glycoprotein known as CD38. The CD38 antigen is expressed on pre-B lymphocytes, plasma cells, thymocytes and monocytes. CD38 also presents on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Antigen expression is detected during the early stage of T- and B-lymphocyte differentiation, then lost during the intermediate stage of maturation, only to reappear during the final stage of maturation. The CD38 antigen is expressed on 90 % of CD34+ cells and is not expressed on pluripotent stem cells. CD38 is expressed in T- and B-acute lymphoblastic leukemia (ALL), Burkitt's lymphoma, multiple myeloma, acute myeloid leukemia (AML), and chronic lymphocytic leukemia (CLL).

Aufreinigung: Purified

Reinheit: >95 %

Güteklasse: GMP Grade

Immunogen: Human acute lymphoblastic leukaemia cells

Klon: OKT10

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Referenzen für anti-CD38 Antikörper (Biotin) (ABIN3071825)

Hammarlund, Thomas, Amanna, Holden, Slayden, Park, Gao, Slifka: "Plasma cell survival in the absence of B cell memory." in: Nature communications, Vol. 8, Issue 1, pp. 1781, (2018) (PubMed).

Details zu CD38

Target: CD38

Abstract: CD38 Produkte

Synonyme: T10 antikoerper, Cd38-rs1 antikoerper, cd38 antikoerper, ADPRC 1 antikoerper, cADPr hydrolase 1 antikoerper, CD38 molecule antikoerper, CD38 antigen antikoerper, CD38 molecule L homeolog antikoerper, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 antikoerper, CD38 antikoerper, Cd38 antikoerper, cd38.L antikoerper

NCBI Accession: NM_001775

UniProt: P28907