Histone H2B Antikörper

Produktnummer ABIN317616

Produktdetails anti-Histone H2B Antikörper

Target: Histone H2B

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500-1/1000. ELISA: 1/5000-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Histone H2B

Target: Histone H2B

Abstract: Histone H2B Produkte

Synonyme: Hist1h2bc antikoerper, H2B antikoerper, HISTONE H2B antikoerper, MRN17.11 antikoerper, MRN17_11 antikoerper, histone B2 antikoerper, H2B1 antikoerper, HIS2B antikoerper, histone cluster 1 H2B family member k antikoerper, histone H2B antikoerper, histone B2 antikoerper, histone H2B.3 antikoerper, Hist1h2bk antikoerper, H2B antikoerper, HTB2 antikoerper, THAPSDRAFT_27352 antikoerper, THAPSDRAFT_37309 antikoerper, THAPS_6947 antikoerper, THAPSDRAFT_34210 antikoerper, LOC426037 antikoerper, LOC107802329 antikoerper

Hintergrund: In eukaryotes, DNA is wrapped around histone octamers to form the basic unit of chromatin structure. The octamer is composed of histones H2A, H2B H3 and H4 and it associates with approximately 200 base pairs of DNA to form the nucleosome. The association of DNA with histones results in dense packing of chromatin, which restricts proteins involved in gene transcription from binding to DNA. Histone H1 is required for the condensation of nucleosome chains into higher order structures. Phosporylation of Histone H1 is thought be involved in this process, although the exact nature of this role has yet to be elucidated. Evidence suggests that Histone H1 is a part of a general repressor mechanism for stable repression of transcription, but it can also activate transcription of specific genes.Synonyms: H2B Histone Family, HIST1H2B

Molekulargewicht: approx. 18 kDa