FZD7 Antikörper
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- Target Alle FZD7 Antikörper anzeigen
- FZD7 (Frizzled Family Receptor 7 (FZD7))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FZD7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects endogenous levels of Frizzled-7 protein.(region surrounding Tyr87)
- Aufreinigung
- Affinity Chromatography.
- Top Product
- Discover our top product FZD7 Primärantikörper
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- Applikationshinweise
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ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % Sodium Azide as preservative, approx. pH 7.2.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Andere Bezeichnung
- FZD7 / Frizzled-7 (FZD7 Produkte)
- Synonyme
- FzE3 antikoerper, Fz-7 antikoerper, Xfz7 antikoerper, frizzled-7 antikoerper, frizzled7 antikoerper, frz-7 antikoerper, frz7 antikoerper, fz7 antikoerper, fzd7-a antikoerper, fzd7-b antikoerper, fze3 antikoerper, Fz7 antikoerper, cFz-7 antikoerper, fb38g02 antikoerper, fc44b09 antikoerper, fz13 antikoerper, fz7a antikoerper, fz7b antikoerper, wu:fb38g02 antikoerper, wu:fc44b09 antikoerper, zg13 antikoerper, frizzled class receptor 7 antikoerper, frizzled class receptor 7 L homeolog antikoerper, frizzled class receptor 7b antikoerper, FZD7 antikoerper, fzd7.L antikoerper, fzd7 antikoerper, Fzd7 antikoerper, fzd7b antikoerper
- Hintergrund
- The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. frizzled-7 has a Lys-Thr-X-X-X-Trp motif which is involved in the activation of the Wnt/beta-catenin signaling pathway. frizzled-7 is an integral membrane protein showing a high expression in adult skeletal muscle, fetal kidney, fetal lung, adult heart, brain and placenta. It is specifically expressed in squamous cell esophageal carcinomas.Synonyms: Fz-7, mFz7
- Gen-ID
- 8324
- NCBI Accession
- NP_003498
- UniProt
- O75084
- Pathways
- WNT Signalweg, Stem Cell Maintenance
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