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REM1 Antikörper

REM1 Reaktivität: Human, Maus, Ratte WB, IF, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN317842
  • Target Alle REM1 Antikörper anzeigen
    REM1 (RAS (RAD and GEM)-Like GTP-Binding 1 (REM1))
    Reaktivität
    • 18
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 29
    • 4
    Kaninchen
    Klonalität
    • 31
    • 2
    Polyklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser REM1 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects endogenous levels of Rad GTPase protein.(region surrounding Leu80)
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product REM1 Primärantikörper
  • Applikationshinweise
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    REM1 (RAS (RAD and GEM)-Like GTP-Binding 1 (REM1))
    Andere Bezeichnung
    REM1 (REM1 Produkte)
    Synonyme
    GD:REM antikoerper, GES antikoerper, E030011C07Rik antikoerper, Rem antikoerper, GEM antikoerper, SI:zK76P14.3 antikoerper, horizin antikoerper, rem antikoerper, zgc:56144 antikoerper, RRAD and GEM like GTPase 1 antikoerper, rad and gem related GTP binding protein 1 antikoerper, RAS (RAD and GEM)-like GTP-binding 1 antikoerper, REM1 antikoerper, Rem1 antikoerper, rem1 antikoerper
    Hintergrund
    The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.Synonyms: GES, GTP-binding protein REM 1, GTPase-regulating endothelial cell sprouting, REM, Rad and Gem-like GTP-binding protein 1
    Molekulargewicht
    approx. 33 kDa
    Gen-ID
    28954
    NCBI Accession
    NP_054731
    UniProt
    O75628
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