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CD44 Antikörper

CD44 Reaktivität: Human IHC (fro) Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN318928
  • Target Alle CD44 Antikörper anzeigen
    CD44
    Reaktivität
    • 299
    • 155
    • 71
    • 31
    • 25
    • 23
    • 14
    • 13
    • 10
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 170
    • 119
    • 92
    • 1
    • 1
    Ziege
    Klonalität
    • 271
    • 110
    • 2
    Polyklonal
    Konjugat
    • 172
    • 43
    • 31
    • 23
    • 17
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD44 Antikörper ist unkonjugiert
    Applikation
    • 280
    • 151
    • 89
    • 78
    • 72
    • 68
    • 57
    • 45
    • 40
    • 30
    • 27
    • 15
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody specifically recognises epitopes encoded by exons v3-v10 on the variant portion of CD44.
    Aufreinigung
    Purified
    Immunogen
    Recombinant human CD44v3-v10
    Isotyp
    IgG
    Top Product
    Discover our top product CD44 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry on frozen sections: 50g/mL. Immunohistochemistry on paraffin sections: 20g/mL, requires antigen retrieval using heattreatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 isrecommended for this purpose. Positive Control: Breast carcinoma and colon adenocarcinoma.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0mg/mL
    Buffer
    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD44
    Andere Bezeichnung
    CD44 (CD44 Produkte)
    Hintergrund
    CD44 is a ubiquitously expressed type 1 transmembrane glycoprotein and proteoglycan, otherwise known as phagocytic glycoprotein 1 (pgp 1), which acts as a receptor for the major extracellular matrix component hyaluronate, and also binds other ligands including collagen and matrix metalloproteinases (MMPs). CD44 is known to play a role in cell-cell interactions, cell adhesion, the activation and homing of lymphocytes, cell migration, haematopoiesis and metastasis, and exists as a number of isoforms generated by the alternative RNA splicing of at least 10 variant exons (CD44v).Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I
    Gen-ID
    960
    NCBI Accession
    NP_000601
    UniProt
    P16070
    Pathways
    Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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