p53 Antikörper (pSer392)
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- Target Alle p53 (TP53) Antikörper anzeigen
- p53 (TP53) (Tumor Protein P53 (TP53))
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Bindungsspezifität
- pSer392
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Reaktivität
- Human, Ratte, Affe
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser p53 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody is specific for p53, when phosphorylated at serine 392.
- Aufreinigung
- Affinity chromatography
- Immunogen
- Synthetic phosphopeptide corresponding to an amino acid sequence within p53 which includes phosphorylated Ser392.
- Isotyp
- IgG
- Top Product
- Discover our top product TP53 Primärantikörper
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- Applikationshinweise
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Western Blot: 1: 1000, recognises a band of approximately 53 kD in rat brain nuclear fractionlysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Andere Bezeichnung
- p53 (TP53) (TP53 Produkte)
- Hintergrund
- The tumour suppressor protein p53, is expressed ubiquitously and plays an important role in blocking proliferation of damaged cells. Phosphorylation of p53 at serine 392 is reported in response to diverse stresses, for example UV irradiation.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
- Gen-ID
- 7157
- NCBI Accession
- NP_000537
- UniProt
- P04637
- Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
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