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CD14 Antikörper (N-Term)

CD14 Reaktivität: Human, Affe FACS, IP, IHC (fro) Wirt: Maus Monoclonal UCHM1 unconjugated

Produktnummer ABIN319685

Datenblatt (PDF)

Target Alle CD14 Antikörper anzeigen

CD14
Bindungsspezifität
9

6

5

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-4, N-Term
Reaktivität
253

45

40

27

24

23

23

23

20

17

16

15

14

14

13

10

8

7

6

5

5

2

1

1
Human, Affe
Wirt
226

52

25

3

1
Maus
Passende Sekundärantikörper
Klonalität
253

54
Monoklonal
Konjugat
123

34

25

20

15

8

6

5

5

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD14 Antikörper ist unkonjugiert
Applikation
231

87

65

57

55

50

22

15

13

12

7

6

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung

Affinity chromatography on Protein G

Immunogen

Human Thymocytes followed by peripheral blood mononuclear cells. Spleen cells from mice immunised with human thymocytes and PBLs were fused with cells from the NS1-Ag4/1 mouse myeloma cell line.

Klon

UCHM1

Isotyp

IgG2a

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anti-CD14 (CD14) antibody (Biotin)
CD14 Reaktivität: Human, Non-Human Primate FACS, WB, ELISA, IP Wirt: Maus Monoclonal MEM-18 Biotin

Applikationshinweise

Flow cytometry. Immunhistology on frozen sections. Recommended Positive Control: Tonsil. Immunprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD14

Andere Bezeichnung

CD14 (CD14 Produkte)

Synonyme

CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper

Hintergrund

CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

Gen-ID

9606

UniProt

P08571

Pathways

TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades