×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
CHEK1 Antikörper
CHEK1
Reaktivität: Human, Maus
WB, ELISA
Wirt: Maus
Monoclonal
2G1D5
unconjugated
Produktnummer ABIN3209997
Produktdetails anti-CHEK1 Antikörper
(ausblenden)
Target
Alle CHEK1 Antikörper anzeigen
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Reaktivität
Alle Reaktivitäten für CHEK1 Antikörper
Human, Maus
Wirt
Alle Wirte für CHEK1 Antikörper
Maus
Klonalität
Alle Klonalitäten für CHEK1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für CHEK1 Antikörper
Dieser CHEK1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CHEK1 Antikörper
Western Blotting (WB), ELISA
Kreuzreaktivität
Maus
Aufreinigung
Purified antibody.
Immunogen
CHK1 antibody was raised in Mouse using a purified recombinant fragment of CHK1 expressed in E. coli as the immunogen.
Klon
2G1D5
Isotyp
IgG1
Top Product
Discover our top product CHEK1 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
ELISA: 1:10,000, WB: 1:500-1:2,000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Konzentration
Lot specific
Buffer
Purified antibody supplied in PBS containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Details zu CHEK1
(ausblenden)
Target
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Andere Bezeichnung
CHK1 (CHEK1 Produkte )
Synonyme
An08g10320 antikoerper, AO090003000441 antikoerper, CHK1 antikoerper, chk1 antikoerper, C85740 antikoerper, Chk1 antikoerper, rad27 antikoerper, id:ibd2720 antikoerper, zgc:56093 antikoerper, CHEK1 antikoerper, checkpoint kinase 1 antikoerper, serine/threonine-protein kinase chk1 antikoerper, serine/threonine-protein kinase Chk1 antikoerper, CAMK/CAMKL/CHK1 protein kinase Chk1 antikoerper, checkpoint kinase 1 S homeolog antikoerper, CHEK1 antikoerper, ANI_1_2436074 antikoerper, AOR_1_768154 antikoerper, PTRG_04183 antikoerper, SJAG_01680 antikoerper, PAAG_04978 antikoerper, MCYG_03290 antikoerper, VDBG_03742 antikoerper, chek1.S antikoerper, Chek1 antikoerper, chek1 antikoerper
Hintergrund
CHK1 is a kinase that phosphorylates Cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Synonyms: Monoclonal CHK1 antibody, Anti-CHK1 antibody, CHK-1 antibody, CHK 1 antibody, CHEK1 antibody.
Pathways
p53 Signalweg , Apoptose , Zellzyklus , DNA Reparatur
Zuletzt angesehen
(ausblenden)