Not reactive in: no confirmed exceptions from predicted reactivity known in the moment
Homologie
Triticum aestivum
Produktmerkmale
Expected / apparent Molecular Weight of the Antigene: 66.3 kDa
Aufreinigung
affinity purified
Immunogen
KLH-conjugated synthetic pepitde chosen from Triticum aestivum ASY1 A7TVU8
Applikationshinweise
1: 1000 (WB), 1: 10 000 (ELISA)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
For reconstitution add 50 μL of sterile water/tube.
Handhabung
Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes. Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Target
ASY1
(DNA-Binding HORMA Protein (ASY1))
Andere Bezeichnung
ASY1
Hintergrund
Pairing and synapsis of homologous chromosomes is required for normal chromosome segregation and the exchange of genetic material via recombination during meiosis. Synapsis is complete at pachytene following the formation of a tri-partite proteinaceous structure known as the synaptonemal complex (SC). In yeast, HOP1 is essential for formation of the SC, and localises along chromosome axes during prophase I. Homologues in Arabidopsis (AtASY1), Brassica (BoASY1) and rice (OsPAIR2) have been isolated through analysis of mutants that display decreased fertility due to severely reduced synapsis of homologous chromosomes. Analysis of these genes has indicated that they play a similar role to HOP1 in pairing and formation of the SC through localisation to axial/lateral elements of the SC.