CA 19-9
Reaktivität: Säugetier
Wirt: Maus
Monoclonal
258-11810
unconjugated
Applikationshinweise
Immunohistochemistry (IHC) for formalin-fixed paraffin embedded (FFPE) tissue sections and frozen sections, the conc. antibodies can be diluted 1:50 -1:100 using polymer or streptavidin -biotin system for 30 mins at room temperature. The Prediluted antibodies are ready to use. The optimum dilution should be determined by the individual lab. Positive Control: Human colon, stomach, pancreas, intestine, breast carcinomas. Cellular Localization: Cytoplasmic.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Target
CA 19-9
(Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
The CA 19-9 antigen is a monosialosyl Le (a) blood group antigen which has been shown to be a useful-associated antigen for the diagnosis of gastrointestinal cancers. This antigen is known to be a ligand for the cell adhesion molecule called ELAM-1 (E-selectin, endothelial cell leukocyte adhesion molecule-1, which is present on cytokine-activated human endothelial cells. Selectin GMP-140 (CD62,PADGEM) binds to sialosyl Le (a) and sulfated glycans modulate this binding.