LRP1 Antikörper

Produktnummer ABIN337070

Produktdetails anti-LRP1 Antikörper

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Marke: IHC-plus™

Spezifität: Recognizes human CD91, a type I membrane protein which is also known as the alpha 2 macroglobulin receptor (alpha 2 MR). Recognizes an epitope in the extracellular region of the 500kD alpha chain.

Aufreinigung: Protein G purified

Immunogen: Purified alpha 2 macroglobulin receptor.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo, IHC, IHC-Fr, IHC-P (5 - 10 μg/mL), IP, WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5-10 μg/mL. Flow Cytometry: 1:50-1:100. Use 10 μL to label 10^6 cells in 100 μL. Western Blot: non-reducing conditions. Positive control: Liver.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Details zu LRP1

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Andere Bezeichnung: LRP1 / CD91 (LRP1 Produkte)

Hintergrund: Name/Gene ID: LRP1

Synonyms: LRP1, Apolipoprotein E receptor, CD91 antigen, CD91, A2MR, IGFBP3R, Alpha-2-macroglobulin receptor, TGFBR5, Type V tgf-beta receptor, APOER, APR, LRP, LRP-1

Gen-ID: 4035

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling