STXBP2 Antikörper (AA 58-70)

Produktnummer ABIN337084

Produktdetails anti-STXBP2 Antikörper

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Bindungsspezifität: AA 58-70

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Hamster, Pferd, Affe, Schwein, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STXBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Marke: IHC-plus™

Spezifität: Recognizes human Munc at ~67kD by Western Blot. Species cross-reactivity: mouse and rat.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum, Platypus, Xenopus (100%) Rabbit, Turkey, Chicken, Salmon, Stickleback, Pufferfish, Zebrafish, Eye worm, Nematode (92%) Lizard (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa 58-70 (V58EDINKRREPIPS70) of human Munc-18. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum, Platypus, Xenopus (100%), Rabbit, Turkey, Chicken, Salmon, Stickleback, Pufferfish, Zebrafish, Eye worm, Nematode (92%), Lizard (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (2.5 μg/mL), IP, WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 1 mg/mL BSA, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu STXBP2

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Andere Bezeichnung: STXBP2 (STXBP2 Produkte)

Hintergrund: Name/Gene ID: STXBP2

Synonyms: STXBP2, Hunc18b, MUNC18-2, Protein unc-18 homolog B, UNC18B, Pp10122, Syntaxin binding protein 2, Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc-18B, UNC18-2

Gen-ID: 6813

UniProt: Q15833

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis