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p53 Antikörper (N-Term)

TP53 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Maus Monoclonal unconjugated

Produktnummer ABIN342253

Datenblatt (PDF)

Target Alle p53 (TP53) Antikörper anzeigen

p53 (TP53) (Tumor Protein P53 (TP53))
Bindungsspezifität
43

40

37

30

29

29

26

26

24

22

20

19

19

19

18

18

16

15

13

9

8

8

8

7

7

6

6

6

6

6

6

6

5

5

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3
N-Term
Reaktivität
834

255

211

107

50

34

33

19

10

9

7

6

6

3

3

3

3

2

2

2

2

1

1

1
Human
Wirt
623

228

6

2

1
Maus
Passende Sekundärantikörper
Klonalität
559

300

1
Monoklonal
Konjugat
484

38

32

19

19

13

13

13

13

13

13

13

13

13

12

12

11

11

11

11

11

11

11

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser p53 Antikörper ist unkonjugiert
Applikation
667

297

250

202

199

149

127

124

119

68

59

35

18

16

13

12

9

9

8

6

4

3

3

3

3

2

2

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Spezifität

Recognizes an epitope within aa 20-25 at the N-terminus of human p53. p53 is a nuclear protein and tumor suppressor that is mutated in a wide variety of cancers. It mediates cell cycle arrest in response to DNA damage, making it important in the maintenance of genomic stability.

Aufreinigung

Protein G purified

Immunogen

Recombinant human p53 expressed in E. coli.

Type of Immunogen: Recombinant protein

Isotyp

IgG2a

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TP53 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7777 unconjugated

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TP53 Reaktivität: Human WB, ELISA, IF, IHC (p), IP Wirt: Maus Monoclonal 2C3 unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 Reaktivität: Human WB, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 2C11 unconjugated

anti-Tumor Protein P53 (TP53) (acLys319) antibody
TP53 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Approved: ELISA (1 - 5 μg/mL), IHC, IP, WB

Kommentare

Target Species of Antibody: Human

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS,  pH 7.4

Handhabung

Avoid freeze/thaw cycles.

Lagerung

-80 °C

Informationen zur Lagerung

Store at -70°C, avoid freeze/thaw cycles.
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Andere Bezeichnung

TP53 / p53 (TP53 Produkte)

Hintergrund

Name/Gene ID: TP53
Family: P53

Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1

Gen-ID

7157

UniProt

P04637

Pathways

p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt