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p53 Antikörper (AA 14-389)

TP53 Reaktivität: Human WB, IHC, IP Wirt: Maus Monoclonal unconjugated

Produktnummer ABIN342254

Datenblatt (PDF)

Target Alle p53 (TP53) Antikörper anzeigen

p53 (TP53) (Tumor Protein P53 (TP53))
Bindungsspezifität
43

40

37

30

29

29

26

26

24

22

20

20

19

19

18

18

16

15

13

9

8

8

8

7

7

6

6

6

6

6

6

6

5

5

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3
AA 14-389
Reaktivität
835

255

211

107

50

34

33

19

10

9

7

6

6

3

3

3

3

2

2

2

2

1

1

1
Human
Wirt
623

229

6

2

1
Maus
Passende Sekundärantikörper
Klonalität
559

301

1
Monoklonal
Konjugat
485

38

32

19

19

13

13

13

13

13

13

13

13

13

12

12

11

11

11

11

11

11

11

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser p53 Antikörper ist unkonjugiert
Applikation
668

298

250

202

200

149

128

124

119

68

59

35

18

16

13

12

9

9

8

6

4

3

3

3

3

2

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Spezifität

Recognizes human p53, a tumor suppressor protein that is mutated in a wide variety of cancers. p53 is a nuclear protein that mediates cell cycle arrest in response to DNA damage which is important in maintaining genomic stability.

Aufreinigung

Protein G purified

Immunogen

Beta galactosidase fusion protein corresponding to aa 14-389 of human p53.

Type of Immunogen: Fusion protein

Isotyp

IgG1

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TP53 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Approved: IHC, IP, WB

Usage: Western Blot, immunoprecipitation, immunohistochemistry, and fluorescence-activated cell sorting: 1-5 μg/mL.

Kommentare

Target Species of Antibody: Human

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS,  pH 7.4

Handhabung

Avoid freeze/thaw cycles.

Lagerung

-80 °C

Informationen zur Lagerung

Store at -70°C, avoid freeze/thaw cycles.
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Andere Bezeichnung

TP53 / p53 (TP53 Produkte)

Hintergrund

Name/Gene ID: TP53
Family: P53

Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1

Gen-ID

7157

UniProt

P04637

Pathways

p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt