CD14 Antikörper (AA 33-44)
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- Target Alle CD14 Antikörper anzeigen
- CD14
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Bindungsspezifität
- AA 33-44
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD14 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Agonist (Agon)
- Spezifität
- Soluble and membrane bound human CD14. The antibody don't block LPS binding to membrane bound CD14.
- Aufreinigung
- Protein A affinity column
- Immunogen
- human Monocytes
- Klon
- BiG4
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD14 Primärantikörper
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- Applikationshinweise
- no significant inhibition of LPS binding to CD14
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with bidistilled water
- Konzentration
- 1 mg/mL
- Buffer
- PBS, pH 7.8
- Konservierungsmittel
- Without preservative
- Lagerung
- -20 °C,-80 °C
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- Target
- CD14
- Andere Bezeichnung
- CD14 (CD14 Produkte)
- Synonyme
- CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper
- Hintergrund
- Background: biG 4 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
- Molekulargewicht
- ~50kDa
- Gen-ID
- 929
- NCBI Accession
- NP_000582
- UniProt
- P08571
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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