LBP Antikörper
(2 Referenzen)-
- Target Alle LBP Antikörper anzeigen
- LBP (Lipopolysaccharide Binding Protein (LBP))
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Reaktivität
- Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LBP Antikörper ist unkonjugiert
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Applikation
- ELISA
- Spezifität
- Mouse LBP. The antibody blocks LPS binding to membrane bound CD14.
- Kreuzreaktivität
- Human, Ratte (Rattus)
- Aufreinigung
- Protein G affinity column
- Immunogen
- native mouse LBP
- Klon
- BiG33
- Isotyp
- IgG1
- Top Product
- Discover our top product LBP Primärantikörper
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anti-Lipopolysaccharide Binding Protein (LBP) (AA 226-480) antibody
LBP Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 224-468) antibodyLBP Reaktivität: Rind (Kuh) WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 25-481) antibodyLBP Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP Reaktivität: Maus ELISA Wirt: Maus Monoclonal biG35 unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP Reaktivität: Human IHC (p) Wirt: Maus Monoclonal biG42 unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C1 unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- ELISA ,LBP inhibition studies, Western Blot. inhibits binding of LPS to membrane bound CD14, (Inhibits LPS-binding (0.5 ug/ml) to CD14+CHO cells (2 x 106/ml) up to 1:1000, total inhibition 1:5 Binding titre at mouse LBP- ELISA: 1:50.000 Cross reacting with rat LBP
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with bidistilled water
- Konzentration
- 1 mg/mL
- Buffer
- PBS, pH 7.17
- Konservierungsmittel
- Without preservative
- Lagerung
- -20 °C,-80 °C
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: "Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).
: "Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes." in: Infection and immunity, Vol. 65, Issue 3, pp. 858-64, (1997) (PubMed).
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: "Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).
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- Target
- LBP (Lipopolysaccharide Binding Protein (LBP))
- Andere Bezeichnung
- Lipopolysaccharide (LPS)-Binding Protein (LBP) (LBP Produkte)
- Synonyme
- BPIFD2 antikoerper, Bpifd2 antikoerper, Ly88 antikoerper, LPSBP antikoerper, LBP antikoerper, lipopolysaccharide binding protein antikoerper, lipopolysaccharide-binding protein antikoerper, LBP antikoerper, Lbp antikoerper, LOC100472839 antikoerper
- Hintergrund
- Background: Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
- Molekulargewicht
- ~58kDa
- Gen-ID
- 16803
- UniProt
- Q61805
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
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