AGR2+AGR3 Antikörper

Produktnummer ABIN343713

Dieses Anti-AGR2+AGR3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von AGR2+AGR3 in WB, ICC und IHC (p). Geeignet für Human.

Kurzübersicht für AGR2+AGR3 Antikörper (ABIN343713)

Target: AGR2+AGR3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AGR2+AGR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: AGR3-4

Produktdetails anti-AGR2+AGR3 Antikörper

Verwendungszweck: Anti-AGR2/AGR3 Purified

Spezifität: The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa), secreted cytoplasmic proteins which can serve as markers of carcinogenesis.

Kreuzreaktivität (Details): Human, Other species Not tested

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Purified human AGR3 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, Positive tissue: human colon.
Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu AGR2+AGR3

Target: AGR2+AGR3

Andere Bezeichnung: AGR2/AGR3

Hintergrund: AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours, AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.,AG2, AG3, HAG2, HAG3