AGR2+AGR3 Antikörper
Reaktivität: Human
WB, ICC, IHC (p)
Wirt: Maus
Monoclonal
AGR3-4
unconjugated
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- Target Alle AGR2+AGR3 Produkte
- AGR2+AGR3
- Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser AGR2+AGR3 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa), secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
- Kreuzreaktivität (Details)
- Human, Other species Not tested
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Purified human AGR3 protein
- Klon
- AGR3-4
- Isotyp
- IgG1
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- Applikationshinweise
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Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, Positive tissue: human colon.
Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- AGR2+AGR3
- Abstract
- AGR2+AGR3 Produkte
- Synonyme
- AG3 antikoerper, BCMP11 antikoerper, HAG3 antikoerper, PDIA18 antikoerper, hAG-3 antikoerper, E030025L21Rik antikoerper, Gm888 antikoerper, anterior gradient 3, protein disulphide isomerase family member antikoerper, anterior gradient 3 antikoerper, AGR3 antikoerper, Agr3 antikoerper
- Hintergrund
- AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours, AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.,AG2, AG3, HAG2, HAG3
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