AMBRA1 Antikörper (N-Term)

Produktnummer ABIN347117

Produktdetails anti-AMBRA1 Antikörper

Target: AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Spezifität: Reacts with mouse 120 kDa Ambra1 protein

Kreuzreaktivität: Ratte (Rattus)

Kreuzreaktivität (Details): Cross reacts with human and rat protein.

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Referenzen für anti-AMBRA1 Antikörper (ABIN347117)

Armstrong, Corazzari, Martin, Pagliarini, Falasca, Hill, Ellis, Al Sabah, Redfern, Fimia, Piacentini, Lovat: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).

Di Bartolomeo, Corazzari, Nazio, Oliverio, Lisi, Antonioli, Pagliarini, Matteoni, Fuoco, Giunta, DAmelio, Nardacci, Romagnoli, Piacentini, Cecconi, Fimia: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, (2010) (PubMed).

Details zu AMBRA1

Target: AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))

Andere Bezeichnung: Activating Molecule in BECN1-Regulated Autophagy Protein 1 (Ambra1) (AMBRA1 Produkte)

Synonyme: 2310079H06Rik antikoerper, A130023A14 antikoerper, AA474864 antikoerper, AV021921 antikoerper, D030051N19Rik antikoerper, mKIAA1736 antikoerper, Nyw1 antikoerper, DCAF3 antikoerper, WDR94 antikoerper, autophagy and beclin 1 regulator 1 antikoerper, autophagy/beclin-1 regulator 1a antikoerper, autophagy/beclin 1 regulator 1 antikoerper, AMBRA1 antikoerper, ambra1a antikoerper, Ambra1 antikoerper

Hintergrund: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation

Gen-ID: 55626

UniProt: Q9C0C7

Pathways: Autophagie