TTC3 Antikörper (N-Term)
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- Target Alle TTC3 Antikörper anzeigen
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TTC3 Antikörper ist unkonjugiert
- Applikation
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- Reacts with human E3 ubiquitin-protein ligase TTC3
- Aufreinigung
- Antiserum
- Immunogen
- Synthetic peptide derived from Cter domain of human TTC3
- Isotyp
- IgG
- Top Product
- Discover our top product TTC3 Primärantikörper
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- Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:100 - 1:500) WB(1:500 - 1:5000) - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Must be reconstituted in distilled water.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Haltbarkeit
- 24 months
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- Target
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
- Andere Bezeichnung
- E3 ubiquitin-protein ligase TTC3 (TTC3 Produkte)
- Synonyme
- DCRR1 antikoerper, RNF105 antikoerper, TPRDIII antikoerper, 2610202A04Rik antikoerper, AA409221 antikoerper, D16Ium21 antikoerper, D16Ium21e antikoerper, TPRD antikoerper, mKIAA4119 antikoerper, TTC3 antikoerper, tetratricopeptide repeat domain 3 antikoerper, E3 ubiquitin-protein ligase TTC3 antikoerper, TTC3 antikoerper, Ttc3 antikoerper, LOC100562480 antikoerper
- Hintergrund
- E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
- UniProt
- P53804
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