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TTC3 Antikörper (N-Term)

TTC3 Reaktivität: Human ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN347721
  • Target Alle TTC3 Antikörper anzeigen
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Bindungsspezifität
    • 3
    • 2
    • 1
    N-Term
    Reaktivität
    • 4
    • 4
    • 3
    Human
    Wirt
    • 5
    • 2
    Kaninchen
    Klonalität
    • 6
    • 1
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    Dieser TTC3 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    Spezifität
    Reacts with human E3 ubiquitin-protein ligase TTC3
    Aufreinigung
    Antiserum
    Immunogen
    Synthetic peptide derived from Cter domain of human TTC3
    Isotyp
    IgG
    Top Product
    Discover our top product TTC3 Primärantikörper
  • Applikationshinweise

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    IF(1:100 - 1:500) WB(1:500 - 1:5000)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Must be reconstituted in distilled water.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Haltbarkeit
    24 months
  • Target
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Andere Bezeichnung
    E3 ubiquitin-protein ligase TTC3 (TTC3 Produkte)
    Synonyme
    DCRR1 antikoerper, RNF105 antikoerper, TPRDIII antikoerper, 2610202A04Rik antikoerper, AA409221 antikoerper, D16Ium21 antikoerper, D16Ium21e antikoerper, TPRD antikoerper, mKIAA4119 antikoerper, TTC3 antikoerper, tetratricopeptide repeat domain 3 antikoerper, E3 ubiquitin-protein ligase TTC3 antikoerper, TTC3 antikoerper, Ttc3 antikoerper, LOC100562480 antikoerper
    Hintergrund
    E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
    UniProt
    P53804
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