Histone H4 Antikörper (ciArg3, N-Term)

Produktnummer ABIN347793

Produktdetails anti-Histone H4 Antikörper

Target: Histone H4

Bindungsspezifität: ciArg3, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: Reacts with human Histone H4 Citrulline at the position 3 (10 kDa)

Kreuzreaktivität (Details): No cross reaction with free H4 nor with other citrullinated proteins. May cross reacts with other species due to sequence homology.

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from Nter region of Human Histone H4, containing Citrulline at position 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA(1:5000 - 1:10000) IHC(1:100 - 1:1000) WB(1:100 - 1:1000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu Histone H4

Target: Histone H4

Abstract: Histone H4 Produkte

Synonyme: hist1h4l antikoerper, H1ft antikoerper, Hist4 antikoerper, Hist4h4 antikoerper, H4 antikoerper, X04652 antikoerper, FO108 antikoerper, H4/n antikoerper, H4F2 antikoerper, H4FN antikoerper, HIST2H4 antikoerper, H4C13 antikoerper, H4C7 antikoerper, F8N16.2 antikoerper, F8N16_2 antikoerper, histone H4 antikoerper, BcDNA:RH52884 antikoerper, CG3379 antikoerper, Dmel\CG3379 antikoerper, H4r antikoerper, His4-88CD antikoerper, His4R antikoerper, histone cluster 1, H4a L homeolog antikoerper, histone cluster 1 H4 family member B antikoerper, histone cluster 2, H4 antikoerper, histone cluster 2 H4 family member a antikoerper, histone H4 antikoerper, Histone H4 replacement antikoerper, Histone H4 antikoerper, hist1h4a.L antikoerper, Hist1h4b antikoerper, Hist2h4 antikoerper, HIST2H4A antikoerper, H4 antikoerper, H4C14 antikoerper, HIS4 antikoerper, HIST2H4 antikoerper, His4r antikoerper, his-38 antikoerper

Hintergrund: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.