Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PTENP1 Antikörper (N-Term)

PTENP1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN349585
  • Target Alle PTENP1 Produkte
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 2
    • 2
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 4
    Dieser PTENP1 Antikörper ist unkonjugiert
    Applikation
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    This affinity-purified antibody is directed against human PTEN-P1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification.  Reactivity occurs against human PTEN-P1 protein.   A BLAST analysis was used to suggest cross reactivity with PTEN proteins from mouse,
    Produktmerkmale
    This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
    Aufreinigung
    affinity purified
    Sterilität
    Sterile filtered
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein.
    Immunogen Type: Peptide
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 55 kDa in size corresponding to PTEN-P1 protein by western blotting in the appropriate cell lysate or extract.
    Kommentare

    Gene Name: PTENP1

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.15 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
    Haltbarkeit
    3 months
  • Target
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Andere Bezeichnung
    PTEN-P1 (PTENP1 Produkte)
    Synonyme
    PTEN-rs antikoerper, PTEN2 antikoerper, PTENpg1 antikoerper, PTH2 antikoerper, psiPTEN antikoerper, phosphatase and tensin homolog pseudogene 1 antikoerper, PTENP1 antikoerper
    Hintergrund
    This gene (PTENP1) is a highly homologous pseudogene of PTEN.  PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
    Synonyms: Phosphatase and tensin homolog pseudogene 1 antibody, psiPTEN antibody, PTEN rs antibody, PTEN2 antibody, PTH2 antibody, TEP1 antibody
    Gen-ID
    5728, 73765544
    UniProt
    O43460
Sie sind hier:
Kundenservice