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PTENP1 Antikörper (N-Term)

Rockland 600-401-a90 PTENP1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN349585
Hersteller Produkt- Nr.: 600-401-a90
  • Target Alle PTENP1 Produkte
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 2
    • 2
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 4
    Dieser PTENP1 Antikörper ist unkonjugiert
    Applikation
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA
    Hersteller Produkt- Nr.
    600-401-a90
    Hersteller
    Rockland
    Verwendungszweck
    PTEN-P1 Antibody
    Kreuzreaktivität (Details)
    This affinity-purified antibody is directed against human PTEN protein.
    Produktmerkmale
    Synonyms: rabbit anti-PTEN-P1 antibody, Phosphatase and tensin homolog 2, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, PTEN, MMAC1, TEP1
    Aufreinigung
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    Sterilität
    Sterile filtered
    Immunogen

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein.

    Immunogen Type: Conjugated Peptide

    Isotyp
    IgG
  • Applikationshinweise

    Application Note: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 55 kDa in size corresponding to PTEN-P1 protein by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500 to 1:2,000

    ELISA Dilution: 1:160,000

    Other: User Optimized

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.15 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Andere Bezeichnung
    PTEN-P1 (PTENP1 Produkte)
    Hintergrund
    Background: This gene (PTENP1) is a highly homologous pseudogene of PTEN.  PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
    Gen-ID
    5728, 73765544
    UniProt
    O43460
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