CHMP3
(Charged Multivesicular Body Protein 3 (CHMP3))
Bindungsspezifität
N-Term
Reaktivität
Human
Wirt
Schaf
Klonalität
Polyklonal
Konjugat
Dieser CHMP3 Antikörper ist unkonjugiert
Applikation
Western Blotting (WB), Immunohistochemistry (IHC)
Spezifität
Specific for CHMP3.
Kreuzreaktivität
Human, Maus, Ratte
Kreuzreaktivität (Details)
Other species not yet tested.
Aufreinigung
IgG
Immunogen
A synthetic peptide from the n-terminal of human CHMP3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
Handhabung
Avoid freeze and thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit
12 months
Target
CHMP3
(Charged Multivesicular Body Protein 3 (CHMP3))
CG9779 antikoerper, Dmel\\CG9779 antikoerper, Vps24 antikoerper, dvps24 antikoerper, vps24 antikoerper, VPS24 antikoerper, CHMP3 antikoerper, GB15107 antikoerper, wu:fb47g01 antikoerper, zgc:76972 antikoerper, NEDF antikoerper, 25.1 antikoerper, 4921505F14Rik antikoerper, 9130011K15Rik antikoerper, CGI-49 antikoerper, D6Ertd286e antikoerper, Vacuolar protein sorting 24 antikoerper, charged multivesicular body protein 3 antikoerper, SNF7 family protein antikoerper, hypothetical protein antikoerper, neuroendocrine differentiation factor, putative antikoerper, charged multivesicular body protein 3 S homeolog antikoerper, Vps24 antikoerper, chmp3 antikoerper, VPS24.2 antikoerper, CpipJ_CPIJ004098 antikoerper, PGTG_02107 antikoerper, LOC5569267 antikoerper, Smp_032150 antikoerper, CHMP3 antikoerper, LOC410607 antikoerper, Chmp3 antikoerper, chmp3.S antikoerper
Hintergrund
FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. Required for sorting/trafficking of EGF receptor. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins. SUBCELLULAR LOCATION: Cytoplasm, cytosol. Membrane, Lipid-anchor. TISSUE SPECIFICITY: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,Vesicle Protein Sorting,Chromatin-modifying protein 3, Vacuolar protein-sorting-associated protein 24, hVps24, Neuroendocrine differentiation factor, Charged multivesicular body protein 3, VPS24, NEDF