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LC3C Antikörper

MAP1LC3C Reaktivität: Human WB, IHC Wirt: Schaf Polyclonal unconjugated
Produktnummer ABIN350463
  • Target Alle LC3C (MAP1LC3C) Antikörper anzeigen
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    Reaktivität
    • 43
    • 3
    • 2
    Human
    Wirt
    • 42
    • 1
    Schaf
    Klonalität
    • 43
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LC3C Antikörper ist unkonjugiert
    Applikation
    • 32
    • 27
    • 9
    • 6
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for MAP1LC3C.
    Kreuzreaktivität
    Human
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from human microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C, MAP1A/MAP1B LC3 C) conjugated to an immunogenic carrier protein has been used as the immunogen.
    Isotyp
    IgG
    Top Product
    Discover our top product MAP1LC3C Primärantikörper
  • Applikationshinweise
    IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    Andere Bezeichnung
    MAP1LC3C (MAP1LC3C Produkte)
    Synonyme
    MAP1LC3C antikoerper, MGC154878 antikoerper, ATG8J antikoerper, LC3C antikoerper, microtubule associated protein 1 light chain 3 gamma antikoerper, microtubule associated protein 1 light chain 3 gamma L homeolog antikoerper, MAP1LC3C antikoerper, map1lc3c antikoerper, map1lc3c.L antikoerper
    Hintergrund
    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane, Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane, Lipid-anchor. Note: LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.,Mammalian Autophagy,Microtubule-associated proteins 1A/1B light chain 3C, MAP1LC3C, MAP1A/MAP1B LC3 C, MAP1A/1B light chain 3 C, MAP1 light chain 3-like protein 3, Autophagy-related protein LC3 C, Autophagy-related ubiquitin-like modifier LC3C
    UniProt
    Q9BXW4
    Pathways
    Autophagie
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