SYT1 Antikörper

Produktnummer ABIN350923

Produktdetails anti-SYT1 Antikörper

Target: SYT1 (Synaptotagmin I (SYT1))

Reaktivität: Maus

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser SYT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for SYTI.

Kreuzreaktivität: Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from mouse Synaptotagmin 1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and human.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Andere Bezeichnung: Synaptotagmin-1 (SYT1 Produkte)

Synonyme: P65 antikoerper, SVP65 antikoerper, SYT antikoerper, CG3139 antikoerper, D. Syt I antikoerper, DSYT antikoerper, DSYT2 antikoerper, DSypt antikoerper, DSyt antikoerper, Dmel\\CG3139 antikoerper, Droso1 antikoerper, Dsyt2 antikoerper, SYT I antikoerper, SYT1 antikoerper, Syt antikoerper, Syt 1 antikoerper, Syt I antikoerper, Syt-1 antikoerper, SytI antikoerper, dSYT antikoerper, dsyt1 antikoerper, dsytI antikoerper, l(2)23AB1 antikoerper, l(2)23Ba antikoerper, l(2)k05909 antikoerper, syt antikoerper, syt 1 antikoerper, syt I antikoerper, syt-1 antikoerper, syt1 antikoerper, sytI antikoerper, AW124717 antikoerper, G630098F17Rik antikoerper, Syti antikoerper, GB20036 antikoerper, DKFZP459P193 antikoerper, svp65 antikoerper, p65 antikoerper, wu:fj41c01 antikoerper, wu:fk56d05 antikoerper, zgc:92899 antikoerper, synaptotagmin 1 antikoerper, Synaptotagmin 1 antikoerper, synaptotagmin I antikoerper, synaptotagmin-1 antikoerper, synaptotagmin, p65 antikoerper, synaptotagmin Ia antikoerper, synaptotagmin 1 L homeolog antikoerper, SYT1 antikoerper, Syt1 antikoerper, Tsp_06980 antikoerper, Tsp_08220 antikoerper, syt1 antikoerper, LOC100533340 antikoerper, syt1a antikoerper, syt1.L antikoerper

Hintergrund: FUNCTION: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner, these are neurexins, syntaxin and AP2. COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Note: Synaptic vesicles and chromaffin granules. TISSUE SPECIFICITY: Predominantly expressed in rostral, phylogenetically younger brain regions, and in some endocrine tissues.,Synaptic Vesicle Traffic,Synaptotagmin-1, Synaptotagmin I, SytI, p65, SVP65

UniProt: P21707

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport