VAMP2 Antikörper (AA 10-60)

Produktnummer ABIN351358

Produktdetails anti-VAMP2 Antikörper

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Bindungsspezifität: AA 10-60

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for VAMP2 and VAMP1.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from AA 10-60 of human VAMP2 conjugated to blue carrier protein was used as the antigen. The VAMP2 peptide shares 93% shared identity with VAMP1. The peptide is homologous in many other species including rat, mouse and xenopus.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, WB. A working concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu VAMP2

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Andere Bezeichnung: VAMP 2 (VAMP2 Produkte)

Synonyme: zgc:73302 antikoerper, wu:fj61c06 antikoerper, VAMP2 antikoerper, vamp2-a antikoerper, xsybi antikoerper, Syb-2 antikoerper, Syb2 antikoerper, sybII antikoerper, RATVAMPB antikoerper, RATVAMPIR antikoerper, SYB antikoerper, SYB2 antikoerper, VAMP-2 antikoerper, syb2 antikoerper, vamp2 antikoerper, xsybii antikoerper, vesicle-associated membrane protein 2 antikoerper, vesicle associated membrane protein 2 antikoerper, vesicle associated membrane protein 2 S homeolog antikoerper, vesicle-associated membrane protein 2 (synaptobrevin 2) antikoerper, vesicle associated membrane protein 2 L homeolog antikoerper, vamp2 antikoerper, VAMP2 antikoerper, vamp2.S antikoerper, Vamp2 antikoerper, vamp2.L antikoerper

Hintergrund: The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. FUNCTION: Involved in the targeting and/or fusion of transport vesicles to their target membrane. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Note: Neuronal synaptic vesicles.,Vesicle Transport,VAMP-2, Synaptobrevin-2, VAMP2, SYB2. VAMP1, Synaptobrevin-1

UniProt: P63027

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport