KDM3B Antikörper (N-Term)
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- Target Alle KDM3B Antikörper anzeigen
- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDM3B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody will recognize JMJD1B (N-term).
- Aufreinigung
- Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human JMJD1B.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product KDM3B Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Western Blot: 1/250-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
- Andere Bezeichnung
- JMJD1B / KDM3B (KDM3B Produkte)
- Synonyme
- KDM3B antikoerper, JMJD1B antikoerper, 5830462I21Rik antikoerper, JHDM2B antikoerper, Jmjd1b antikoerper, mKIAA1082 antikoerper, 5qNCA antikoerper, C5orf7 antikoerper, NET22 antikoerper, lysine demethylase 3B antikoerper, lysine (K)-specific demethylase 3B antikoerper, lysine-specific demethylase 3B antikoerper, KDM3B lysine (K)-specific demethylase 3B antikoerper, KDM3B antikoerper, LOC100540242 antikoerper, kdm3b antikoerper, Kdm3b antikoerper
- Hintergrund
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: 5qNCA, C5orf7, JHDM2B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, KIAA1082, Lysine-specific demethylase 3B, Nuclear protein 5qNCA
- Gen-ID
- 51780, 9606
- UniProt
- Q7LBC6
- Pathways
- Warburg Effekt
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