Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

JMJD4 Antikörper (C-Term)

JMJD4 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN356562
  • Target Alle JMJD4 Produkte
    JMJD4 (Jumonji Domain Containing 4 (JMJD4))
    Bindungsspezifität
    • 8
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 26
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 26
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser JMJD4 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 15
    • 8
    • 4
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody will recognize JMJD4 (C-term). It Cross reacts with Mouse (Predicted by 100 % Antigen Homology).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human JMJD4.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    ELISA: 1/1,000. Western Blot: 1/250-1/500. Immunohistochemistry: 1/10approx. 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    JMJD4 (Jumonji Domain Containing 4 (JMJD4))
    Andere Bezeichnung
    JMJD4 (JMJD4 Produkte)
    Synonyme
    JMJD4 antikoerper, 6430559I23 antikoerper, RGD1307186 antikoerper, jumonji domain containing 4 antikoerper, jumonji domain containing 4 L homeolog antikoerper, JMJD4 antikoerper, jmjd4.L antikoerper, Jmjd4 antikoerper
    Hintergrund
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: JmjC domain-containing protein 4, Jumonji domain-containing protein 4
    Gen-ID
    65094, 9606
    UniProt
    Q9H9V9
Sie sind hier:
Kundenservice