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UBA3 Antikörper (C-Term)

UBA3 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN356593
  • Target Alle UBA3 Antikörper anzeigen
    UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
    Bindungsspezifität
    • 8
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 31
    • 21
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 30
    • 1
    Polyklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBA3 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 17
    • 14
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific to UBE1C (C-term). Predicted to cross react with Mouse and DANRE (100 % Antigen Homology).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UBE1C.
    Isotyp
    Ig Fraction
    Top Product
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  • Applikationshinweise
    ELISA: 1/1,000. Western blot: 1/100approx. 1/500. Immunohistochemistry: 1/50approx. 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
    Andere Bezeichnung
    UBA3 / UBE1C (UBA3 Produkte)
    Synonyme
    UBE1C antikoerper, hUBA3 antikoerper, Ube1c antikoerper, ube1c antikoerper, wu:fb75e04 antikoerper, wu:fc37b11 antikoerper, zgc:55528 antikoerper, A830034N06Rik antikoerper, AI256736 antikoerper, AI848246 antikoerper, AW546539 antikoerper, ubiquitin like modifier activating enzyme 3 antikoerper, ubiquitin-like modifier activating enzyme 3 antikoerper, ubiquitin like modifier activating enzyme 3 S homeolog antikoerper, UBA3 antikoerper, Uba3 antikoerper, uba3 antikoerper, uba3.S antikoerper
    Hintergrund
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Synonyms: NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme 3, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3
    Gen-ID
    9039, 9606
    UniProt
    Q8TBC4
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