NCOR1 Antikörper (N-Term)

Produktnummer ABIN356671

Produktdetails anti-NCOR1 Antikörper

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific to NCOR1 (N-term).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NCOR1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: NCOR1 (NCOR1 Produkte)

Synonyme: ncor antikoerper, zgc:56355 antikoerper, 5730405M06Rik antikoerper, A230020K14Rik antikoerper, N-CoR antikoerper, RIP13 antikoerper, Rxrip13 antikoerper, mKIAA1047 antikoerper, N-CoR1 antikoerper, TRAC1 antikoerper, hN-CoR antikoerper, nuclear receptor corepressor 1 antikoerper, nuclear receptor co-repressor 1 antikoerper, nuclear receptor corepressor 1 pseudogene antikoerper, nuclear receptor corepressor 1 S homeolog antikoerper, ncor1 antikoerper, NCOR1 antikoerper, CpipJ_CPIJ002507 antikoerper, LOC100343278 antikoerper, Ncor1 antikoerper, ncor1.S antikoerper

Hintergrund: NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.Synonyms: KIAA1047, N-CoR, N-CoR1, Nuclear receptor corepressor 1

Gen-ID: 9611, 9606

UniProt: O75376

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process