PUMA Antikörper (BH3 Domain, C-Term)
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- Target Alle PUMA (BBC3) Antikörper anzeigen
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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Bindungsspezifität
- BH3 Domain, C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PUMA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody is specific to Human and Mouse PUMA (BH3 Domain). Other species not tested.
- Aufreinigung
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogen
- Synthetic peptide selected from the C-terminal region of Human PUMA
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product BBC3 Primärantikörper
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anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody
BBC3 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 131-180) antibodyBBC3 Reaktivität: Human, Ratte, Schwein WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 Reaktivität: Human WB, FACS, IHC (p), IF Wirt: Kaninchen Polyclonal RB01353 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 Reaktivität: Human WB, ELISA, IHC, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibodyBBC3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PE)BBC3 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal PE
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PerCP)BBC3 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal PerCP
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibody (Biotin)BBC3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal Biotin
anti-BCL2 Binding Component 3 (BBC3) (AA 109-137) antibodyBBC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33714 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 98-152) antibodyBBC3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5D10 unconjugated
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- Applikationshinweise
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ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Andere Bezeichnung
- PUMA (BBC3 Produkte)
- Synonyme
- BBC3 antikoerper, Puma antikoerper, JFY-1 antikoerper, JFY1 antikoerper, PUMA antikoerper, PUMA/JFY1 antikoerper, BCL2 binding component 3 antikoerper, Bcl-2 binding component 3 antikoerper, BBC3 antikoerper, Bbc3 antikoerper, bbc3 antikoerper
- Hintergrund
- PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.Synonyms: BBC3, Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis
- Molekulargewicht
- 20532 Da
- Gen-ID
- 27113, 9606
- UniProt
- Q9BXH1
- Pathways
- p53 Signalweg, Positive Regulation of Endopeptidase Activity
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