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DKK3 Antikörper (N-Term)

Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN357071
  • Target Alle DKK3 Antikörper anzeigen
    DKK3
    Bindungsspezifität
    • 15
    • 9
    • 9
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 54
    • 35
    • 17
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 66
    • 5
    • 2
    • 1
    Kaninchen
    Klonalität
    • 67
    • 7
    Polyklonal
    Konjugat
    • 33
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DKK3 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 38
    • 29
    • 13
    • 13
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects DKK3 at N-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DKK3.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DKK3 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    DKK3
    Andere Bezeichnung
    Dickkopf-3 (DKK3) (DKK3 Produkte)
    Synonyme
    REIC antikoerper, RIG antikoerper, reic antikoerper, dkk-3 antikoerper, AW061014 antikoerper, C87148 antikoerper, Reic antikoerper, p29 antikoerper, dickkopf WNT signaling pathway inhibitor 3 antikoerper, dickkopf WNT signaling pathway inhibitor 3 S homeolog antikoerper, DKK3 antikoerper, dkk3 antikoerper, dkk3.S antikoerper, Dkk3 antikoerper
    Hintergrund
    DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and heart.Synonyms: Dickkopf-related protein 3, Dkk-3, REIC
    Molekulargewicht
    38291 Da
    Gen-ID
    27122
    NCBI Accession
    NP_001018067
    UniProt
    Q9UBP4
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