UBE4B Antikörper (N-Term)

Produktnummer ABIN357483

Produktdetails anti-UBE4B Antikörper

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects UBE4B at N-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBE4B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu UBE4B

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Andere Bezeichnung: UBE4B (UBE4B Produkte)

Synonyme: ufd2a antikoerper, E4 antikoerper, HDNB1 antikoerper, UBOX3 antikoerper, UFD2 antikoerper, UFD2A antikoerper, 4930551I19Rik antikoerper, 4933406G05Rik antikoerper, AU014668 antikoerper, D4Bwg0973e antikoerper, UFD2a antikoerper, Ufd2p antikoerper, mKIAA0684 antikoerper, ubiquitination factor E4B antikoerper, putative ubiquitin conjugation factor E4 B antikoerper, ubiquitin conjugation factor E4 B antikoerper, ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) antikoerper, Ube4b antikoerper, LINJ_30_1070 antikoerper, LBRM_30_1130 antikoerper, Tsp_12732 antikoerper, Tsp_01624 antikoerper, ube4b antikoerper, UBE4B antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.Synonyms: HDNB1, Homozygously deleted in neuroblastoma 1, KIAA0684, UFD2, Ubiquitin conjugation factor E4 B, Ubiquitin fusion degradation protein 2

Molekulargewicht: 133275 Da

Gen-ID: 10277, 9606

UniProt: O95155