UBE2B Antikörper (C-Term)

Produktnummer ABIN357490

Produktdetails anti-UBE2B Antikörper

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific to UBE2B/RAD6B (C-term). Predicted to cross react with Mouse and Rat (100 % Antigen Homology).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UBE2B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu UBE2B

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Andere Bezeichnung: UBE2B / RAD6B (UBE2B Produkte)

Synonyme: E2-17kDa antikoerper, HHR6B antikoerper, HR6B antikoerper, RAD6B antikoerper, UBC2 antikoerper, e2-17kda antikoerper, hhr6b antikoerper, hr6b antikoerper, rad6b antikoerper, ubc2 antikoerper, zgc:100921 antikoerper, 2610301N02Rik antikoerper, E2-14k antikoerper, Rad6b antikoerper, mHR6B antikoerper, ubiquitin conjugating enzyme E2 B antikoerper, ubiquitin-conjugating enzyme E2B antikoerper, ubiquitin-conjugating enzyme E2B (RAD6 homolog) antikoerper, ubiquitin conjugating enzyme E2 B S homeolog antikoerper, UBE2B antikoerper, Ube2b antikoerper, ube2b antikoerper, ube2b.S antikoerper

Substanzklasse: Viral Protein

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100 % identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.Synonyms: E2-17 kDa, HR6B, Ubiquitin carrier protein B, Ubiquitin-conjugating enzyme E2 B, Ubiquitin-protein ligase B, hHR6B

Molekulargewicht: 17312 Da

Gen-ID: 7320, 5874

UniProt: P63146