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USP8 Antikörper (C-Term)

USP8 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN357535
  • Target Alle USP8 Antikörper anzeigen
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Bindungsspezifität
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 35
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 32
    • 2
    • 1
    Kaninchen
    Klonalität
    • 33
    • 2
    Polyklonal
    Konjugat
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser USP8 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 15
    • 13
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific to USP8/UBPY (C-term). Predicted to cross react with Mouse (100 % Antigen Homology).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human USP8.
    Isotyp
    Ig Fraction
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  • Applikationshinweise
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Andere Bezeichnung
    USP8 / UBPY (USP8 Produkte)
    Synonyme
    HumORF8 antikoerper, UBPY antikoerper, AI574262 antikoerper, AW557536 antikoerper, Ubpy antikoerper, mKIAA0055 antikoerper, ubiquitin carboxyl-terminal hydrolase 8 antikoerper, ubiquitin specific peptidase 8 antikoerper, LOC9310109 antikoerper, MGYG_00369 antikoerper, USP8 antikoerper, Usp8 antikoerper
    Hintergrund
    USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.Synonyms: Deubiquitinating enzyme 8, KIAA0055, Ubiquitin carboxyl-terminal hydrolase 8, Ubiquitin thioesterase 8, Ubiquitin-specific-processing protease 8
    Molekulargewicht
    127523 Da
    Gen-ID
    9101, 5874
    UniProt
    P40818
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